Jun-Jie (Gogo) Liu
PI
Associate professor
Beijing Advanced Innovation Center for Structural Biology
Center of Life Sciences
School of Life Sciences
Tsinghua University
junjiegogoliu(at)tsinghua.edu.cn
Please replace (at) with @ for contact
Manager
Lab Manager
Email: mmli(at)mail.tsinghua.edu.cn
Postdoctoral Associates
Zheng Zhang
Email: zhengzhang61(at)mail.tsinghua.edu.cn
Research Topic:
Developing and optimizing RNA-based nucleic acid editing tools.
Editing is not manipulation but only guidance for the genome to fix itself.
Yuanyuan Jiang
Email: jiangyyuan(at)mail.tsinghua.edu.cn
Research Topic:
(1) Exploring the mechanisms and biological functions of ribozymes;
(2) Developing novel RNA-based nucleic acid manipulation tools within animal and plant organisms.
Mingyang Cui
Research Topic:
I focus on the exploration of biological problems related to non-coding RNAs, including the mining of gene editing tools related to non-coding RNAs, and the regulation of neurodevelopment by long non-coding RNAs
Shuai Jin
Research Topic:
I) Directed evolution of the entire human or plant genomes.
II) Specificity of precise genome editing systems.
III) Evolutionary trajectory of CRISPR systems.
Ao sun
Email: sunao20(at)mails.tsinghua.edu.cn
Research Topic:
1) Developing new CRISPR-Cas gene editing tools
2) Searching novel CRISPR-Cas associated factors
3) Exploring other potential gene editing tools
Graduate Students
Shunqing Tan
Ph.D. Candidate
Email: tansq21(at)mails.tsinghua.edu.cn
Research Topic:
Exploring the mechanism of nuclease activities and developing novel gene editing tools.
Shuo Lin
Ph. D. Candidate
Email:lins23(at)mails.tsinghua.edu.cn
Research Topic:
Mining new ribozyme in matagenomic database and using structual biology approach to solve the mechenism
Yun Yang
Ph.D. Candidate
Email: yangyun19(at)mails.tsinghua.edu.cn
Research Topic:
My major research interest is the direct evolution of Cas proteins in mammalian cells to improve gene editing efficiency based on structural optimization.
Longqi Li
Ph. D. Candidate
Email: lilq22(at)mails.tsinghua.edu.cn
Research Topic:
Detection of gene-editing potential of novel nucleases in mammalian cells and Development of the next-generation gene-manipulating toolbox.
![mmexport1605609348461[1].jpg](https://static.wixstatic.com/media/105bd6_07221a6d898548b6911c5e7fe70fc4b5~mv2.jpg/v1/crop/x_0,y_60,w_673,h_673/fill/w_180,h_180,al_c,q_80,usm_0.66_1.00_0.01,enc_avif,quality_auto/mmexport1605609348461%5B1%5D.jpg)
Zixian Liu
Ph.D. Candidate
Email: liuzx21(at)mails.tsinghua.edu.cn
Research Topic:
My research focuses on the biochemistry analysis and identification of introns to explore their biological functions and their potential to be used in nucleic acid manipulation.
Shulin Jin
Ph. D. Candidate
Email: jsl23(at)mails.tsinghua.edu.cn
Research Topic:
Exploring the mechanism of novel RNA-involved nuclease system by using biochemistry methods.
Gaoli Wang
Ph.D. Candidate
Email: wanggl23(at)mails.tsinghua.edu.cn
Research Topic:
Searching for ribozymes with novel functions and exploring their applications as biological tools
Ruihan Zhang
Ph. D. Candidate
Email: ruihan-z23(at)mails.tsinghua.edu.cn
Research Topic:
Leverage bioinformatics and AI techs to integrate sequence, structure, and evolutionary information for developing next-generation gene editing tools
Xiaozheng Yang
Ph.D. Student
Email: yxz24(at)mails.tsinghua.edu.cn
Explore new functions and possibilities of RNA and ribozymes.
Yang Yi
Ph.D. Student
Email: yiy24(at)mails.tsinghua.edu.cn
I am focused on investigating protein diversity using bioinformatics and deep learning, including predicting proteins in the future and the past.
Jingbo Jiang
Ph. D. Candidate - joint PhD. student
Email: jiangjb18(at)mails.tsinghua.edu.cn
Research Topic:
(1) Studying on physiological RNA substrate of RNA exosome complex in direct-access route by biochemistry and structure;
(2) Exploring new cofactors of RNA exosome complex in yeast and human cells and determining the complex structures.
Staff
Zhonghao Zhang
Email: zhonghaozhang2022(at)163.com
I graduated from Ocean University of China with a master's degree. I am currently working as a research assistant. I am easy-going, sincere, ready to help others, serious and responsible for work.
Undergraduate Students
Jiantao Zhang
Tsinghua University
Grade 2023
Zhehao Zhang
Tsinghua University
Grade 2023
Alumni
Postdoc and Ph.D.
Yuqian Zhao
2020.5-2022.6, Postdoc
Zhihang Chen
2022.3-2024.3, Postdoc
Current, the Qingdao Institute of Bioenergy and Bioprocess Technology, Chinese Academy of Sciences
Pujuan Deng
2020.5-2024.11, Postdoc
Current, Postdoc in Department of Biochemistry in Stanford University
Shouyue Zhang
2020.9-2024.11, Postdoc
Current, PI in Institute of Microbiology, Chinese Academy of Sciences
Mingzhe Xia
2022.01-2025.01, joint Phd
Chengping Li
2020-2025, Ph.D.
![mmexport1605609323137[1].jpg](https://static.wixstatic.com/media/105bd6_7cb6021337b847e7ab5fe2128ef44d36~mv2.jpg/v1/crop/x_0,y_51,w_1080,h_1339/fill/w_121,h_150,al_c,q_80,usm_0.66_1.00_0.01,enc_avif,quality_auto/mmexport1605609323137%5B1%5D.jpg)
Danyuan Li
2020-2025, Ph.D.
Hanzhou Zhu
2020-2025, Ph.D.
Other alumni
Dandan Sun
2020.4-2021.7, Lab Manager
Xinyi Wu
2020.10-2021.4, Visiting Student
Zhuoyan Hai
2020.10-2021.8, Visiting Student
Tingxuan Yang
2021.5-2021.11, Visiting Scholar
Zhihao Jing
2021.9-2022.7, Visiting Scholar
Qiaoyang Ma
2021.9-2022.8, Visiting Student
Jiahui Zhao
2020.10-2021.8, Visiting Scholar
Yutao Chen
2021.10-2022.7, Visiting Student
SweeHong Ng
2023.9-2024.4, Undergraduate Student
Yue Zhang
2023.8-2024.6, Visiting Student
Matylda Zuzanna Klos
2023.9-2024.7, Visiting Student
Yuntian Yang
2024.1-2024.6, Visiting Student
Wenwen Wang
2024.2-2025.2, Visiting Student
Runheng Zhang
2023.4-2024.9, Undergraduate Student
Yun Liu
2021.9-2025.6, Undergraduate Student
Qiyu Yang
2021.9-2025.6, Undergraduate Student
Zhaofu Li
2021.9-2025.6, Undergraduate Student
