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Research

Things we are focusing on

Develop Novel Macromolecular Tools

We are leveraging macromolecules—proteins, RNAs, and RNA-protein complexes (RNPs)—to develop innovative molecular tools for nucleic acid manipulation and detection. Building on our prior work with R2 retrotransposons for gene insertion, HYER for protein-free DNA cleavage, and novel CRISPR-Cas systems for gene editing, our goal is to create new tools, explore uncharted application areas, and enhance existing systems for greater precision and efficiency.

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AI for Life Sciences

We employ computational approaches to model genome diversity, simulate evolutionary processes, and investigate how artificial intelligence and robotics can transform the future of life sciences research, unlocking new possibilities in data analysis and experimental design.

From Structure to Function

Our research focuses on elucidating the structural mechanisms driving key biological systems, including prokaryotic immune systems, ribozymes, and retrotransposons, to deepen our understanding of their functional roles and potential applications.

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©2022 by Gogo Liu Lab at Tsinghua

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